Brief Job Profile Description Join RMC at a pivotal stage in its growth and help shape the engineering systems that enable reliable, compliant, and resilient commercial cell therapy manufacturing. In this highly visible role, you will provide engineering leadership and lifecycle ownership for manufacturing, laboratory, facility, utility, and GMP infrastructure assets—translating complex challenges into practical solutions that protect product quality, patient supply, safety, capacity, and business continuity. You will lead technical and capital initiatives and collaborate across the cell therapy network to advance common standards, digital integration, and engineering excellence. Because these capabilities support continuous manufacturing operations, the role participates in a shared 24/7 on-call support model. Typical Accountabilities Support operational teams as the trusted technical owner and subject matter expert for 700+ manufacturing, laboratory, facility, and utility assets, shaping priorities and fit-for-purpose solutions aligned with site governance and standards. Guide the complete equipment lifecycle—from user requirements, risk assessment, technology selection, and procurement through installation, digital integration, commissioning, qualification, release, operation, maintenance, calibration, reliability improvement, relocation, and decommissioning. Turning complex equipment challenges into lasting improvements by leading troubleshooting, root-cause analysis, technical investigations, change management, and sustainable corrective actions for equipment failures, deviations, data-integrity, reliability, and performance risks, informed by asset, maintenance, alarm, historical, quality, and vendor data. Raise the standard for engineering excellence by establishing and sustaining requirements for automation/OT, alarm management, critical operating parameters, reliability, maintenance strategies, and engineering drawings while ensuring compliance with cGMP, quality, validation, data integrity, SHE, documentation, audit, and inspection expectations. Lead high-impact equipment and capital projects from concept through closeout, owning the business case, technical scope, schedule, cost, risk, resources, vendors, qualification and validation interfaces, turnover, benefits realization, and approved budgets within delegated authority. Inspire and align engineers, technicians, contractors, and cross-functional teams through matrix leadership, reviewing deliverables, mentoring colleagues, influencing decisions, and partnering across the site to achieve operational readiness and reliable return to service. Drive exceptional service and accountability across 60+ vendor agreements supporting critical manufacturing, quality control laboratory, and warehouse equipment by defining requirements, setting expectations, monitoring KPIs, leading escalations, and ensuring delivery against AstraZeneca standards. Help shape the future of the cell therapy manufacturing network by standardizing equipment, specifications, digital integration, lifecycle practices, and technical solutions, while enabling technology and equipment transfers, lessons learned, training, knowledge sharing, and adoption of network standards. Apply artificial intelligence and system and equipment data to uncover root causes, anticipate risk, strengthen reliability, and advance real-time process control. Qualifications and Skills Essential: Bachelor’s degree in Engineering, Life Sciences, or a related technical discipline, or an equivalent combination of education and relevant experience. Minimum of 5 years working in a cGMP biotechnology, pharmaceutical, cell therapy, or other regulated manufacturing environment. Knowledge of engineering principles and equipment lifecycle management, including validation, automation/OT interfaces, digital integration, maintenance, calibration, reliability, change management, and decommissioning. Demonstrated ability to work independently, navigate competing priorities, solve technical problems, and lead cross-functional delivery with sound judgment, influence, and coordination. Desirable: Hands-on experience with robotic systems integrated with third-party manufacturing equipment; experience applying artificial intelligence to process execution is highly valued. Experience contributing to cross-site standardization, equipment or technology transfer, network change management, or other multi-site technical initiatives. Key Relationship to Reach Solutions Internal: Quality; Manufacturing; Maintenance; Metrology; Validation/CQV; Automation/OT; IT; MS&T; SHE; Supply Chain; Procurement; Finance; Capital Projects; site governance; and cell therapy network partners. External: OEMs; equipment and service suppliers; calibration and maintenance providers; system integrators; engineering, construction, and CQV partners; auditors; regulators. The annual base pay (or hourly rate of compensation) for this position ranges from $108,194.40 - $162,291.60. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 20-Oct-2026 Closing Date 12-Nov-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

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