- Bioinformatic analysis of multi-omics data with focus on single-cell and spatial transcriptomics RNA sequencing data to elucidate the tumor microenvironment and its influence on cancer progression and metastasis in renal cell carcinoma
- Integrating multi-omics data sets (e.g. genomics, metabolomics) of primary tumors and metastasis through innovative bioinformatics analysis applicable to high-dimensional data
- Integrated analysis of clinical phenotypes and -omics data using biostatistics and bioinformatics
- Application of a broad spectrum of established tools and development of new computational solutions with focus on single-cell and spatial transcriptomics RNA seq and data integration
- Enthusiasm to present scientific results at international conferences and writing papers for high-quality publications to ensure greatest possible success in your career track
- Doctoral degree (PhD) in bioinformatics, applied bioinformatics or a related discipline
- Experience and strong background in the analysis of spatial transcriptomics and single-cell RNA sequencing data, as well as multi-omics datasets (e.g. proteomics, transcriptomics, genomics), including data interpretation.
- Strong interest in life science applications with focus on oncology and personalized medicine
- Strong programming skills in R and in Python
- Solid background in cancer biology
- Knowledge in biostatistics would be beneficial
- Excellent English written and oral communication skills, as well as expertise in preparation of scientific manuscripts.
We offer:
- The opportunity to work in an interactive team of bioinformaticians, clinicians and biologists.
- State-of-the-art equipment and technologies for a wide range of different applications (genomics, transcriptomics, metabolomics) and expert knowledge within the different core facilities (e.g. core facility “Biostatistics/Bioinformatics, Pharmacometrics and Digital Science”) at the institute
- The opportunity to communicate scientific results at international conferences and to participate in workshops
- An initial contract for 3 years and flexible starting date (earliest starting date as of now)
For further information please contact Prof. Dr. Matthias Schwab (phone 0711-8101-3700) or Dr. Elke Schaeffeler (phone 0711-8101-3729).
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