The University of Nevada, Reno (UNR) appreciates your interest in employment at our growing institution. We want your application process to go smoothly and quickly. Final applications must be submitted prior to the close of the recruitment. If you need assistance or have questions regarding the application process, please contact our recruitment helpline at (775) 784-1495 or jobs@unr.edu. For UNR Med professional job postings, please contact the Office of Professional Recruitment at (775) 784-6778. Job Description The Gut–Brain Science Laboratory, led by Dr. Rajan Singh in the Department of Physiology and Cell Biology at the University of Nevada, Reno School of Medicine, is seeking a highly motivated and collaborative Postdoctoral Scholar to join an NIH-funded research program investigating the cellular and molecular mechanisms underlying gastroparesis, gastrointestinal dysmotility, intestinal barrier dysfunction, and disorders of gut–brain interaction. The successful candidate will contribute to a newly funded NIH R01 investigating how gut-resident macrophages regulate gastric neuromuscular function and epithelial barrier integrity in gastroparesis. The project integrates mechanistic studies in genetically engineered mouse models with translational studies using human gastric and duodenal biopsies. The research program combines neurogastroenterology, mucosal immunology, gastrointestinal physiology, molecular biology, single-cell transcriptomics, advanced imaging, and translational human tissue studies to identify disease mechanisms and develop macrophage-directed therapeutic strategies. The postdoctoral scholar will have opportunities to develop an independent research direction within the overall program, publish high-impact manuscripts, present findings at national and international scientific meetings, participate in multidisciplinary collaborations, and develop skills needed for progression toward an independent research career. Research Responsibilities The successful candidate will work closely with Dr. Singh and collaborating investigators to: Design and conduct mechanistic studies examining the role of muscularis and mucosal macrophages in gastroparesis, gastrointestinal motility, and epithelial barrier dysfunction. Conduct in vivo gastrointestinal physiology studies, including gastric emptying and gastrointestinal transit measurements. Perform intestinal and gastric barrier-function studies using approaches including Ussing chamber/TEER and permeability assays. Isolate and characterize gut-resident immune-cell populations from gastrointestinal tissues. Perform flow cytometry, immunohistochemistry, confocal microscopy, qPCR, Western blotting, ELISA and related molecular and cellular assays. Participate in single-cell RNA sequencing, miRNA profiling and CyTOF-based immune phenotyping, including preparation of biological samples and interpretation of resulting datasets. Participate in translational studies involving coded human gastric and duodenal biopsy specimens obtained through collaborating clinical investigators. Prepare manuscripts, abstracts, and present research findings at laboratory meetings and scientific conferences. Collaborate with faculty, research staff, students, core facilities, and external investigators involved in the program. Required Qualifications Ph.D., M.D./Ph.D., or equivalent doctoral degree in physiology, cell and molecular biology, immunology, neuroscience, gastroenterology, pharmacology, biomedical sciences or a closely related discipline. Demonstrated experience in experimental biomedical research. Excellent written and oral communication skills. Ability to work both independently and collaboratively within a multidisciplinary research environment. Evidence of scientific productivity, such as peer-reviewed publications, manuscripts or substantial doctoral research accomplishments. Completion of a doctoral degree in the appropriate discipline is required. The doctoral degree must have been completed within the five years immediately preceding the first date of appointment as a postdoctoral fellow at the University. The individual cannot have held previous positions in the professional ranks. Preferred Qualifications Experience in one or more of the following areas is highly desirable: Gastrointestinal physiology, neurogastroenterology or GI motility Macrophage biology, mucosal immunology or neuroimmune interactions Transgenic/conditional mouse models and mouse colony management In vivo mouse experimentation Flow cytometry, immunohistochemistry and confocal fluorescence microscopy, single-cell RNA sequencing, CyTOF or high-dimensional immune profiling, Ussing chamber, TEER or epithelial permeability measurements Molecular biology techniques including RNA isolation, qPCR, Western blotting and ELISA Candidates are not expected to possess expertise in every technique listed above. Applicants with strong training in gastrointestinal physiology, immunology, neuroscience, molecular biology or related areas who are interested in developing expertise in neurogastroenterology are particularly encouraged to apply. Compensation Grade Postdoctoral Scholar To view the salary schedule for this position, please visit: Salary Schedules. Salary is competitive and commensurate with related education and experience. Department Information https://med.unr.edu/directory/departments/physiology-cell-biology ExemptYes Full-Time Equivalent100.0% Required Attachment(s) Please note, once you submit your application the only attachment/s viewable to you will be the attachment/s to the resume/CV section of the application. Any additional required attachment/s to the cover letter, references, additional documents sections of the application, will not be viewable to you after you submit your application. All uploaded attachment/s will be on the application for the committee to review. To request updates to attachments, prior to the committee review of applications, please contact the candidate helpdesk at jobs@unr.edu Attach the following attachments to your application 1) Curriculum vitae 2) Cover letter describing previous research experience, scientific interests, and career goals 3) Contact information for three professional references 4) Representative publications This posting is open until filled Qualified individuals are encouraged to apply immediately. This search will close without notice when a sufficient number of applications are received or a hiring decision has been made. Posting Close Date Note to Applicant A background check will be conducted on the candidate(s) selected for hire. HR will attempt to verify academic credentials upon receipt of hiring documents. If the academic credentials cannot be verified, HR will notify the faculty member that an official transcript of their highest degree must be submitted within thirty days of the faculty member’s first day of employment. References will be contacted at the appropriate phase of the recruitment process. Applicants hired on a federal contract may be subject to E-Verify. As part of the hiring process, applicants for positions in the Nevada System of Higher Education may be required to demonstrate the ability to perform job-related tasks. For positions that require driving, evidence of a valid driver's license will be required at the time of employment and as a condition of continued employment. Schedules are subject to change based on organizational needs. University of Nevada, Reno School of Medicine The University of Nevada, Reno is the state of Nevada’s leading public research university. Founded in 1874 as Nevada’s original land-grant university, the University serves more than 24,000 undergraduate and graduate students from all 50 states and 63 countries. Classified by the Carnegie® Classification of Institutions of Higher Education as an R1 (“Very High Research”) university, it is also recognized in the Carnegie® Community Engagement classification. The University is ranked by U.S. News & World Report among the “Best National Universities” and “Best National Public Universities.” It also ranks in the top tier of the Wall Street Journal/Times Higher Education World University Rankings and the New York Times’ “Top Colleges for Economic Diversity.” Since 2009, nearly $1 billion has been invested in advanced labs, facilities and residence halls on the main campus. The University is home to Nevada’s first medical school – the University of Nevada, Reno School of Medicine and the University of Nevada, Reno at Lake Tahoe in Incline Village, Nevada, where education, research and creative work thrive in a stunning mountain setting. The University delivers on its original land-grant mission with outreach across the state through the University of Nevada, Reno Extension, Nevada Agricultural Experiment Station, Nevada Bureau of Mines and Geology, Nevada Small Business Development Center, the Nevada Seismological Laboratory and Wolf Pack Athletics. The main campus is in Reno, Nevada, a growing technology hub with a vibrant midtown and downtown. Founded where the high desert of the Great Basin meets the High Sierra and Lake Tahoe, the University’s beautiful, 290-acre main campus is also a Nevada state arboretum. The University’s physical infrastructure continues to expand, with the opening of the John Tulloch Business Building as well as the completion of a new state public health laboratory with groundbreaking for a life sciences building scheduled for 2027. The University has also invested in affordable housing for faculty and staff with its University Village, a series of fully renovated housing parcels located near campus. Collaborating with world-renowned organizations, the University fosters innovation through initiatives such as the Digital Wolf Pack partnership with Apple and Microsoft, which ensures equitable access to technology for students, providing new incoming freshman or transfer students with a new devices and accessories. Through its commitment to high-impact education, world-improving research and creative activity, and outreach that’s transforming Nevada’s communities and businesses, the University continues its 150-year tradition of benefitting our state, nation and world. Just one example is how the University is leading the way in the nation’s effort to develop new, clean energy sources that will power the country’s future through its selection as one of the inaugural 31 Regional Technology and Innovation Hubs (TechHubs) through the U.S. Department of Commerce’s Economic Development Administration. Nevada’s Tech Hub strengthens America’s lithium batteries, critical elements and other electric vehicle materials industry sectors within the state. The University recognizes that diversity promotes excellence in education and research. The inclusive and engaged community on campus recognizes the added value that students, faculty and staff from different backgrounds bring to the educational experience. Today, the University delivers on its original land-grant mission of access to education and knowledge by investing in the academics, facilities, support, engagement and vibrant campus life that promote our diverse students’ cognitive growth and academic achievement – all while remaining one of the best values in American higher education. For more information, please visit the University’s website. NSHE is committed to providing a place of work and learning free of discrimination on the basis of a person’s age (40 or older), disability, whether actual or perceived by others (including service-connected disabilities), gender (including pregnancy related conditions), military status or military obligations, sexual orientation, gender identity or expression, genetic information, national origin, race (including hair texture and protected hairstyles such as natural hairstyles, afros, bantu knots, curls, braids, locks and twists), color, or religion (protected classes). Center for Civil Rights & Equal Access Zeva Edmondson Director, Title IX Coordinator Center for Civil Rights and Equal Access 1664 N. Virginia Street Reno, NV 89557 (775) 784-1547 eotix@unr.edu The University of Nevada, Reno, does not discriminate on the basis of sex in any education program or activity that it operates. Non-discrimination on the basis of sex is mandated by Title IX of the Education Amendments of 1972 (20 U.S.C. §§ 1681 et seq.) and the corresponding implementation regulations (34 C.F.R. Part 106). The University’s commitment to nondiscrimination in its education programs and activities extends to applicants for admission and employment. Inquiries concerning the application of these provisions may be referred to: Zeva Edmondson, Director, Title IX Coordinator, Center for Civil Rights and Equal Access, University of Nevada, Reno, 1664 N. Virginia Street, Continuing Education Building, Room 206, m/s 158, Reno, Nevada 89557-0158, Telephone: (775) 784-1547; Email: eotix@unr.edu; to The Assistant Secretary of the United States Department of Education, U.S. Department of Education, Office for Civil Rights, 400 Maryland Avenue, SW, Washington, D.C. 20202-1100; Telephone: 1-800-421-3481 FAX: 202-453-6012; TDD: 1-800-877-8339; Email: OCR@ed.gov; or to both. Information pertaining to the University’s grievance procedures and grievance process, including how to report or file a complaint of sex discrimination, how to report or file a formal complaint of sexual harassment, and how the University will respond can be found here. If you need any accommodations to complete an application, please contact Human Resources at jobs@unr.edu. Si necesita alguna acomodación para completar una solicitud, comuníquese con Recursos Humanos en jobs@unr.edu. Information regarding security, personal safety, fire safety, and crime statistics can be found at UNR's website. NSHE Employees are required to participate in a mandatory retirement plan in lieu of Social Security. As a result, employment at NSHE may impact your Social Security benefits. Additional information is available at SSA 1945. Job postings are specific to the Nevada System of Higher Education.

Postdoctoral Scholar, Physiology and Cell Biology (Gut–Brain Science Laboratory).

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