Senior Scientist, Cell Therapy Introduction to role Are you ready to turn cutting-edge cell engineering into therapies that reshape how cancer is treated? As a Senior Scientist, Cell Therapy based in Gaithersburg, MD, you will drive critical product and process characterization that informs design decisions, accelerates candidates to the clinic, and ultimately impacts patients who need new options most. You will join a fast-moving, collaborative lab environment where change is constant and curiosity is expected. Do you thrive when working with unknowns, translating complex datasets into clear direction, and partnering across disciplines to move science forward with pace and precision? This role offers the opportunity to see your bench work translate into program strategy and clinical progress. Accountabilities Product and process characterization: Design and execute hands-on studies that define attributes of cellular therapies and underpin robust, scalable processes. Analytical readouts: Lead characterization of cellular products using multicolor flow cytometry, ELISA, dPCR, karyotyping, microscopy, biomarker and cytokine analyses, and -omics approaches to generate decision-ready data. Data translation and communication: Assess, synthesize, and report findings with clarity and urgency; ensure insights are relayed efficiently for forward translation into program plans. Experimental design and troubleshooting: Independently plan, optimize, and troubleshoot experiments to meet milestones and de-risk development. Cross-functional collaboration: Partner closely with project managers and adjacent teams to align assay strategy, timelines, and deliverables with program needs. Scientific impact in drug discovery: Interpret results within the broader mechanism and development context to shape next experiments and guide program direction. Documentation and quality: Maintain rigorous records and high data integrity to support quality, compliance, and reproducibility. Essential Skills/Experience PhD in a relevant subject area with 0-3 years of demonstrated experience in Cellular Therapy, Cell Biology, Cell engineering, Bioinformatics, Immunology, and/ or Immuno-Oncology; M.S. with 5+ years’ experience; B.S. with 10+ years’ experience Extensive in vitro skillset for cell characterization such as functional/potency assays, morphological/phenotypic assessment, and sequencing based methods. Multicolor flow cytometry, microscopy, biomarker and cytokine analysis, ELISA, dPCR, karyotype and -omics. Experience analyzing large process and characterization data sets using a breadth of statistical methods including machine learning algorithms. Well-developed understanding of molecular and cellular biology (specifically immune cell physiology), immunological assays, and cell transfection/transduction. Proficiency in cell culture and aseptic techniques. Ability to design, execute, troubleshoot, and document experiments; to review, analyze, interpret results; and communicate deliverables in a timely manner. Desirable Skills/Experience Experience with genome editing technologies (CRISPR/Cas9, base-editing, virus-based genetic delivery systems, etc.). In vitro experience isolating and culturing human T cells. Basic experience developing cellular therapies including CAR-T therapies. Proficiency with statistical software (JMP, R, etc.). Working cross-functionally to drive project advancement. Why AstraZeneca Here, bold science meets practical impact: you will work in modern labs alongside immunologists, bioengineers, data scientists, and manufacturing experts—often in the same room—sparking ideas that move from bench to clinic with speed. We embrace ambiguity, take calculated risks, and learn fast, because patients cannot wait. Your contributions will be visible and valued across programs, with leaders who empower you to shape methods, challenge assumptions, and pursue smarter routes through complex problems. We value kindness alongside ambition, pairing rigorous standards with a supportive, feedback-rich culture so you can grow while delivering therapies that matter. Bring your expertise to Gaithersburg and help deliver the next generation of cell therapies—step forward today and shape science into patient benefit! The annual base pay for this position ranges from $112,304 to $168,456. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans Date Posted 16-Oct-2026 Closing Date 30-Oct-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

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