This is what you will do: The Head of Strategic Initiatives & Operations will report into the VP of US Value and Access. This position is responsible for owning initiatives that require cross-functional, above brand coordination, both internal and external to the US Value and Access organization. This role is based at Alexion’s Boston headquarters. You will be responsible for: Create executive-level narratives and recommendations for senior leadership endorsement and cross-functional alignment of key priorities Leading or setting up task forces to take on strategic initiatives, such as AI initiatives, launch ways of working, business review, etc. Assessing and informing the market access organization of new capabilities / innovation that can improve the efficiency and effectiveness of the US Value and Access organization Leads in the impact modeling of environmental shifts and marketplace dynamics on the Alexion portfolio of medicines Acting as the market access lead on cross-functional initiatives with teams outside of the US Value and Access organization (e.g. Strategic Account Leads, sales organization, Patient Services, BOCE, etc.) Ensure effective governance process and organize major meeting schedule for Market Access team Co-lead with VP Market Access development of annual operating plan (focus on FTE and project spend) Lead all market access-wide internal meetings, training and compliance initiatives Manage market access budget activities including working closely with Finance Identify interdependencies and connections between departments and ensure integrated end-to-end visibility and alignment. You will need to have: Bachelor’s Degree or the equivalent in Life Sciences, Business, or a related field 10+ years of related and/or transferable experience in a biotech or pharma company Ability to complete quantitative and qualitative analyses of complex business proposals Strong understanding of relevant U.S. regulations and policies Demonstrated ability to effectively communicate complex business challenges and data-driven recommendations to senior leaders Knowledge of the US market access landscape as well as subject matter expertise of Market Access organizations We would prefer you to have: MBA or other advanced degree Must have project management experience and excellent analytical, strategic thinking, creativity and problem-solving skills Expresses industry knowledge and acumen including Rare Disease experience Strong communication skills and ability to work with cross-functional teams Ability to work under pressure, in a fast-paced environment Must exhibit strong leadership skills Advanced computer skills (Excel, Power Point and Microsoft Project) The annual base pay for this position ranges from $186,105.60 - 279,158.40 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Date Posted 22-Oct-2026 Closing Date 28-Oct-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

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