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CRA II/Senior CRA - Early Phase ICON is a global healthcare intelligence and clinical research organisation united by a mission to bring new medicines and treatments to patients faster. As a values-driven organisation, integrity, collaboration, agility, and inclusion are at the heart of how we work and interact with each other, customers, patients and suppliers. As a CRA II or Senior CRA within our Early Phase team, you'll play a critical role in studies that sit at the very beginning of the drug development journey, including first-in-human and proof-of-concept research. Working alongside leading investigators, sponsors, and specialist clinical teams, you'll help advance promising new therapies from concept to clinical reality. Unlike traditional large-scale monitoring roles, you'll focus on a smaller portfolio of approximately 3-4 sites across the UK, enabling you to build strong site relationships, maintain exceptional quality oversight, and make a genuine impact on the success of each study. What You'll Be Doing Managing site qualification, initiation, monitoring and close-out activities across a portfolio of UK Early Phase studies. Building strong partnerships with investigators and site teams to ensure study success. Ensuring patient safety, protocol compliance, and data integrity throughout the clinical trial lifecycle. Reviewing study data, resolving site queries, and proactively identifying and mitigating risks. Supporting sponsors and project teams through the unique operational challenges associated with early development programmes. Acting as a trusted clinical research expert, providing guidance and support to sites and internal stakeholders. What We're Looking For CRA II: Previous independent monitoring experience across clinical trials. Senior CRA: Significant independent monitoring experience with the ability to manage complex studies and act as a mentor for less experienced colleagues. Strong understanding of ICH-GCP, regulatory requirements, and clinical trial operations. Excellent relationship-building and communication skills. Ability to work proactively, independently, and collaboratively within a global study team. Life Science, Nursing, Pharmacy, or other relevant healthcare degree (or equivalent experience). Able to travel across the UK as required to complete onsite visits Employment with ICON is contingent upon having the legal right to work in the country where the role is based. Rewards & Benefits ICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development. Benefits may include: Competitive base salary and performance related incentives Health and wellbeing programmes including medical, dental, and vision coverage where applicable Retirement and pension plans Life assurance and disability coverage Employee assistance programmes and wellbeing resources Learning and development opportunities through structured training and career pathways Benefits may vary depending on role and location. Visit our careers site to read more about the benefits ICON offers. Inclusion and Accessibility ICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported. If you require reasonable accommodations during the recruitment process, please let us know or submit a request here. Are you a current ICON Employee? Please click here to apply ICON is an award-winning workplace that enables you to make a difference to patients’ lives by being part of a world-class clinical research organisation that helps deliver new medicines & medical devices that are benefitting patients worldwide. You are also part of a diverse company that cares about our world and is dedicated to conducting business more sustainably and supporting the communities in which we live. If you’re as driven as we are, join us. You’ll be working in a great environment, with some of the brightest and the friendliest people in the sector, and you’ll be helping shape an industry. Didn’t find the role you were looking for? Even if the perfect role isn’t available right now, we’re always excited to connect with talented individuals. Register to our Talent Community to receive updates on roles that align with your career goals. 
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UK
CRA II.
REMOTE
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