Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH. Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way. Head of Market Access – Italy Location: Milan Summary The Head of Market Access, reporting to the VP, General Manager, will play a pivotal leadership role in ensuring Italian patients gain timely and sustainable access to Madrigal’s innovative therapies. This role defines and executes the national market access and pricing strategy, drives engagement with Italian authorities and payers, and shapes the local access environment in alignment with Madrigal’s global access vision. Working collaboratively with Medical, Regulatory, HEOR, Commercial, and Regional and Global Access colleagues, this leader will help translate science into access, ensuring the value of innovation is recognized across the Italian healthcare system. Acting as an enterprise leader, the incumbent will demonstrate patient focus in every decision, act with an owner mindset, champion innovation, and foster collaboration to drive impact and advance Madrigal’s purpose of leading the fight against MASH. Key Responsibilities Lead and execute the market access and pricing strategy for Italy, with primary accountability for securing national reimbursement and appropriate access for Rezdiffra. Lead the AIFA pricing and reimbursement process, including dossier development, authority interactions and negotiations, in close collaboration with the General Manager and Regional and Global Access teams. Create strategies to successfully navigate the current negotiation environment, including cost-containment pressures and MFN considerations, appropriately positioning Rezdiffra to achieve reimbursement that reflects its value for patients with advanced MASH. Lead key stakeholder engagement to communicate the urgency of treating patients with advanced MASH and build awareness of the therapeutic benefits Rezdiffra can offer, developing strong relationships with AIFA, payers, clinicians, KOLs and patient organizations. Partner with Medical, Regulatory, HEOR, Commercial and Access colleagues to develop compelling value propositions, evidence plans and market access tools that support reimbursement and payer engagement. Develop and execute early access strategies, including opportunities such as CNN, to support timely patient access ahead of full reimbursement. Prepare for effective regional access following national reimbursement, building the stakeholder relationships, tools and plans required to translate the national outcome into patient access across Italy. Monitor the evolving Italian pricing, reimbursement, policy and competitive environment and adapt access strategies accordingly. Build and lead the Italian Market Access team as the organization evolves, establishing clear priorities, capabilities and ways of working to support national and regional access. Serve as a member of the Country Leadership Team, contributing to launch readiness, brand strategy and long-term market shaping while fostering cross-functional collaboration and ensuring compliance. Profile Strategic and forward-looking leader with a strong understanding of the Italian healthcare environment and the ability to translate complexity into clear priorities and action. Strong collaborator, influencer, and negotiator who builds credibility and drives alignment across internal teams and external stakeholders. Entrepreneurial and hands-on mindset, with the agility, accountability, and sense of urgency to thrive in a fast-moving, growing organization. Passionate about improving patient access and motivated by Madrigal’s purpose to make a meaningful difference in patients’ lives. Qualifications University degree in Life Sciences, Health Economics, Public Health, Business, or a related discipline; advanced degree preferred. 8+ years of Market Access, Pricing, Reimbursement, or HEOR experience within the Italian pharmaceutical or biotechnology sector. Proven success navigating AIFA pricing and reimbursement processes for innovative medicines, including direct involvement in pricing negotiations. Deep knowledge of the Italian healthcare system, including national and regional payer dynamics, HTA, reimbursement, and early access mechanisms, with a strong network of relevant stakeholders. Demonstrated ability to develop and execute strategies addressing complex pricing, reimbursement, and access challenges. Strong cross-functional leadership and ability to operate effectively in international, matrixed environments. Excellent communication, influencing, negotiation, and presentation skills. Fluency in Italian and English Willingness to travel within Italy and internationally as required. We are committed to fostering an inclusive and diverse workplace and do not discriminate on the basis of any legally protected characteristics. Madrigal processes your personal data in connection with its recruitment and talent sourcing activities in accordance with applicable data protection laws. Further information about how your personal data is processed, together with details of your rights and how to exercise them, is available in our Job Applicant Privacy Notice, which is made available to you if you apply through Workday. Please note that this job description is not exhaustive and may evolve over time. Only shortlisted candidates will be contacted. Applicants must be authorized to work in the country of employment at the time of application. Employment terms, where applicable, will be governed by relevant collective bargaining agreements. Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. Join our growing team focused on transforming the treatment of people with liver diseases. Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

Head of Market Access, Italy.

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