Job Purpose The Senior Manager, CSO PMO is the head of governance for the CSO PMO and owns the CSO Delivery Framework, its standards, controls and operating processes. The role provides enterprise-wide oversight of projects delivered by CSO project and programme resources, ensuring consistent governance, transparent decision-making and disciplined delivery across the portfolio. It leads the evolution of the framework through automation, simplification and continuous process improvement, while providing authoritative challenge, assurance and insight to CSO leadership. About the team The CSO PMO is the governance and portfolio management authority for the Cyber Security Office project portfolio. It establishes the delivery framework used by CSO project and programme resources, governs intake, prioritisation, planning, financial control, risk, assurance and reporting, and gives leadership an integrated view of delivery performance, capacity, dependencies and outcomes across a global, matrixed and regulated function. Key responsibilities: This role will provide you the opportunity to lead key activities to progress your career. These responsibilities include some of the following: Own, govern and continuously evolve the CSO Delivery Framework, defining the mandatory lifecycle, standards, controls, decision rights, artifacts and minimum evidence required for consistent delivery. Act as the head of governance for the entire CSO PMO, establishing portfolio governance forums, operating rhythms, escalation routes and clear accountabilities across projects and programmes. Provide independent oversight and constructive challenge to projects run by CSO delivery resources, assuring adherence to the framework without assuming day-to-day project management accountability. Govern portfolio intake, prioritisation, sequencing and roadmap integration so that investment and resource decisions align with CSO strategy, risk priorities and available capacity. Set expectations for project planning and control across scope, milestones, dependencies, resources, financials, risks, issues, change, quality, benefits and closure. Lead portfolio-level assurance, identifying systemic delivery risks, control gaps and underperformance, and driving timely decisions, recovery actions and escalations. Own the integrated CSO delivery plan and executive governance reporting, providing a single, reliable view of progress, forecast, capacity, dependencies, risk and benefits. Advance automation of PMO workflows, controls, data collection, reporting and management insight to improve accuracy, timeliness and scalability. Drive simplification and process improvement, removing unnecessary bureaucracy while retaining proportionate controls appropriate to cyber security and a regulated environment. Define portfolio data standards and performance measures, strengthen data quality and use analysis and visualisation to enable evidence-based governance decisions. Lead, coach and develop PMO governance capability, ensuring practitioners and delivery resources understand and consistently apply the CSO Delivery Framework. Build trusted relationships with CSO leaders, finance, risk, quality, technology and delivery partners, resolving cross-portfolio issues and improving interfaces across organisational boundaries. Why you? We are looking for professionals with the following required skills to achieve our goals: Basic Qualifications: Bachelor’s degree or equivalent relevant experience. Substantial experience leading portfolio, programme or enterprise PMO governance in a complex global organisation. Demonstrated ownership of a delivery framework, methodology or governance operating model, including standards, controls, assurance and adoption. Strong portfolio and programme management acumen across prioritisation, integrated planning, financial management, resource and capacity planning, risk, dependency, change and benefits governance. Proven ability to provide independent oversight, constructive challenge and clear escalation across multiple projects without displacing accountable delivery leaders. Experience designing and implementing process automation, reporting improvements and simplified governance workflows. Strong analytical, financial and commercial acumen, with the ability to translate complex delivery data into clear executive insight and recommendations. Experience operating in cyber security, technology, pharmaceutical, life sciences or another highly regulated environment. Proven leadership, coaching, stakeholder management, influencing and communication skills across senior, cross-functional and geographically dispersed teams. Ability to balance pace, rigour and risk, simplify complex processes and drive sustained adoption of common ways of working. Preferred Qualifications: Deep knowledge of cyber security delivery or significant experience working within a Cyber Security Office. Advanced capability in data analysis, visualisation and executive reporting using Excel, Power BI or comparable tools. Experience with workflow automation, low-code platforms, AI-enabled reporting or integration of portfolio management toolsets. Track record of leading PMO transformation, governance simplification, process redesign and measurable continuous improvement. Experience embedding Agile, product, programme and traditional delivery approaches within a proportionate enterprise governance model. Project, programme, portfolio or Agile certification such as PMP, PgMP, PfMP, MSP, PRINCE2 or SAFe. Experience working across a global matrix and influencing senior leaders through evidence, judgement and trusted challenge. Typical tools and technologies: enterprise portfolio and work management platforms such as ServiceNow, Jira, Planview or Clarity; Excel and Power BI; workflow automation and low-code tools; data integration, governance reporting and visualisation capabilities. #GSKcso Closing date for applications: 19th November 2026 Skills Change Management, Compliance Risk Management, Dependency Analysis, Executive Reports, Financial Acumen, Portfolio Performance Management, Portfolio Prioritization, Problem Solving, Project Management Governance, Shareholder Communications, Stakeholder Management Why GSK? Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. We believe in an agile working culture for all our roles. If flexibility is important to you, we encourage you to explore with our hiring team what the opportunities are. Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities contact us at [email protected] where you can also request a call. Please note should your enquiry not relate to adjustments, we will not be able to support you through these channels. However, we have created a Recruitment FAQ guide. 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For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/ We are a global biopharma company with a special purpose – to unite science, technology and talent to get ahead of disease together – so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns – as an organisation where people can thrive. Getting ahead means preventing disease as well as treating it, and we aim to impact the health of 2.5 billion people around the world in the next 10 years. Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves – feeling welcome, valued and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together. Find out more on our career site.

Senior Manager, Cyber Security Office PMO.

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