Are you a passionate individual with expertise in mathematical modelling and pharmacokinetics/pharmacodynamics (PK/PD)? Do you want to apply quantitative approaches to help shape the development of future treatments for cardiovascular, renal and metabolic diseases? If so, we invite you to join our Modelling & Simulation team within the Early Cardiovascular, Renal and Metabolism (CVRM) therapeutic area at AstraZeneca. This position is based at our dynamic R&D site in Gothenburg, Sweden. Accountabilities: As a Modelling and Simulation PK/PD expert, you will play a key role in shaping project strategies and driving critical decisions across our drug discovery portfolio. You will actively contribute to drug project teams, providing quantitative insights to inform target and molecule selection, dosing strategies, and translational development decisions. You will design and oversee the execution of complex studies in preclinical disease models, applying advanced mathematical modelling approaches to deliver impactful PK/PD and translational insights. Your expertise will enable you to synthesize data from multiple sources, predict human pharmacokinetics and pharmacodynamics, and influence the definition of efficacious exposure and dosing regimens. In this role, you will present and defend your quantitative assessments and recommendations to internal governance and senior stakeholders, shaping critical decisions at the highest levels. You will also provide scientific leadership by initiating and leading strategic DMPK and PK/PD innovation projects, fostering collaboration across disciplines, and representing AstraZeneca’s modelling expertise both internally and within the broader scientific community. Essential Skills/Experience: PhD in pharmacokinetics, pharmacology, mathematics, or related field, with a focus on model-based PK/PD approaches. Industry or academic experience in exposure-response modelling such as PK/PD, NLME, PBPK and/or QSP, with hands-on experience using relevant modelling and programming tools (e.g., Phoenix, R, MATLAB, Python, Monolix, NONMEM) Demonstrated ability to integrate complex data, apply quantitative reasoning, and translate modelling results into recommendations that inform project decisions Demonstrated scientific leadership and a strong track record of scientific contributions in a relevant area Experience applying AI and machine learning to quantitative research workflows, for example in data curation, PK/PD modelling or translational modelling Excellent communication and influencing skills, with the ability to present complex quantitative results clearly to cross-functional teams and senior stakeholders Desirable Skills/Experience: Experience applying PK/PD modelling in a preclinical or translational setting Experience developing quantitative modelling strategies across multiple therapeutic modalities such as small molecules, oligonucleotides, peptides, proteins, antibodies or cell and gene therapies Experience in PBPK modelling using platforms such as Simcyp or PK-Sim At AstraZeneca, we are driven by results and use our unique blend of science and commercial knowledge to spot opportunities and drive outcomes. We are part of an expansive healthcare ecosystem that connects key players across the entire patient journey. Our patient-first approach informs every decision we make. We are committed to your development and believe that your best is better here. Join us and be part of a global team of curious, collaborative colleagues. Ready to make your mark? Apply now and be a part of our journey to redefine the future of healthcare! We welcome your application by November 17, 2026. Date Posted 04-nov.-2026 Closing Date 17-nov.-2026 Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

Modelling and Simulation PK/PD Expert.

more at Astrazeneca.

Head of Diagnostics - ANZ

Senior Director- Global Development Scientist

Manager, Market Access Policy Implementation

similar roles.

Jefe de Mantenimiento

ROG Reseller Ops - Luzon

DSP - 2nd Shift

Direct Support Professional (DSP) / Caregiver