Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), a serious liver disease that can progress to cirrhosis, liver failure, need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH. Madrigal’s medication, Rezdiffra (resmetirom), is a once-daily, oral, liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c). Our success is driven by our people. We are building a dynamic, inclusive, and high-performing culture that values scientific excellence, operational rigor, and collaboration. To support our continued growth, we are strengthening our workforce strategy to ensure we have the right talent, at the right time, in the right way. We are seeking a proactive, highly organized Senior Administrative Assistant to support key business operations, communications, and team coordination activities. This role requires a strong blend of traditional administrative expertise (calendar, travel, and expense support) along with light project management, team collaboration, and event planning skills. The ideal candidate will demonstrate sound judgment, discretion, and an ability to operate independently in a dynamic, fast-paced environment. Key Responsibilities · Manage complex calendars, prioritize and schedule meetings (internal and external), and anticipate scheduling needs across time zones. · Coordinate domestic and international travel arrangements and prepare expense reports (using Concur). · Serve as an operational extension of the team, helping to manage communications, ensure alignment around key activities, and support execution across the span of delegation. · Support internal communications and team collaboration by capturing input and turning team-building or planning discussions into tangible outputs and action steps. · Assist in coordinating and planning department meetings, workshops, and events—including offsite logistics, venue selection, agendas, and follow-ups. · Maintain department files, records, and shared resources with accuracy and confidentiality. · Monitor and reinforce adherence to internal processes, policies, and key deadlines. · Collaborate with other administrative staff to ensure continuity, support cross-functional efforts, and drive cohesion across departments. · Prepare, edit, and distribute presentations, spreadsheets, memos, and meeting notes as needed. · Provide support for small-scale projects as assigned, including status tracking and stakeholder coordination. Qualifications · Associate degree preferred · 6–8 years of administrative support experience in a corporate environment, preferably in a life sciences setting. · Demonstrated experience managing executive calendars, travel arrangements, and expense reports. · Proficiency in Microsoft Office Suite (Outlook, Word, Excel, PowerPoint); experience with Concur strongly preferred. · Excellent written and verbal communication skills; able to interact professionally with internal and external stakeholders. · Strong organizational and project coordination skills, with a proven ability to manage multiple tasks simultaneously. · Discretion, sound judgment, and the ability to maintain confidentiality are essential. · Collaborative, team-oriented approach with a proactive and flexible mindset. · Willingness to travel occasionally for offsite meetings and events. · This role will require 3 days per week onsite in Waltham, MA. Madrigal’s Total Rewards strategy is based on a biotech industry peer group comparator and is inclusive of base pay, bonus and equity. Our equity offers meaningful opportunity allowing our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization. All employees receive equity, which we believe reinforces our ownership culture. Base salary is determined by several factors including the candidate’s qualifications, skills, education, experience, business needs and market demands. As of the date of this posting, a good faith estimate of the current pay scale for this position, applicable to all candidates, is $90,829 - $111,013 per year. We comply with all applicable minimum wage laws. All full-time employees receive equity, which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance, we empower employees to think like owners, giving them a stake in the organization. Full-time employees are also eligible for comprehensive benefits, including flexible paid time off, medical, dental, vision and life/disability insurance, and 401(k) offerings (i.e., traditional, Roth, and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance, legal services, and other offerings. In addition, we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal, state, and local laws. We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance, please contact [email protected]. Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law. Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established. Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site. Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals’ Hiring Managers, seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigal’s name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype, RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g., fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process. Please also note that any correspondence with regard to employment would come from an authorized madrigalpharma.com email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses, with Madrigal misspelled, have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal, we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to [email protected]. Join our growing team focused on transforming the treatment of people with liver diseases. Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications, merit, and business need. Applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex gender identity, sexual orientation, national origin, age, disability, protected veteran or disabled status, or other characteristic protected by applicable federal, state, or local law.

Senior Administrative Assistant.

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