At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters. The Position The Evidence Solution Leader (ESL) is a critical role within Product Development Medical Affairs (PDMA), responsible for designing and implementing strategic, global Real-World Evidence (RWE) solutions and overseeing local RWE solutions, to address prioritized gaps identified in the Integrated Evidence Plan (IEP). This is a strategic medical role that provides expertise in RWE generation, insight generation, scientific engagement, external collaborations and affiliate enablement, with a focus on optimizing evidence solution design and implementation. By maximizing data utility, enhancing the value proposition of therapies, and increasing the visibility and impact of RWE, the ESL ensures evidence strategies are grounded in foresight and tailored to the evolving needs of patients, healthcare professionals, and decision-makers. The Opportunity: You serve as a medical and methodological expert for Real-World Data (RWD) and data reuse, supporting prioritized DAs, asset teams, and affiliates You lead the design of RWE solutions that are fit-for-purpose, decision-driven, and aligned with strategic priorities across the lifecycle You contribute to IEPs by recommending optimal RWE solutions, including reuse of data assets, Non-Interventional Studies (NIS) and RWD scientific projects You ensure RWE solutions enable early visibility, support value differentiation, and are relevant across global and local contexts You proactively identify and drive opportunities for data reuse across studies, systems, and geographies and promote transparency of internal data assets and tools that enable future reuse You partner with cross-functional stakeholders (medical, access, clinical, commercial, data science) and affiliates to align on evidence needs and feasibility You enable affiliates by co-creating local and multi-country RWE solutions, sharing expertise, and promoting use of standardized frameworks and tools You create and sustain a community of local Evidence Generation Leaders focused on capability building, data landscaping, RWD initiatives, and data reuse Who you are: You have an advanced degree in a relevant scientific field (MD, PhD, PharmD, or equivalent in life sciences, epidemiology, public health, health economics, or related discipline) with 7+ years of experience in the pharmaceutical, biotechnology, or healthcare industry, with at least 3-5 years in conceptualization, design and implementation of strategic evidence generation solutions including real-world data (RWD), or non-interventional study (NIS) leadership roles You have demonstrated experience contributing to or leading integrated evidence plans (IEPs) or equivalent cross-functional strategic planning You have global or multi-country experience in medical affairs, clinical development, health outcomes, or RWE You have a deep understanding of real-world evidence methodologies, including study design, data sources (EHR, claims, registries, etc.), analytical approaches, interpretation and scientific communication and bring knowledge of data privacy, governance, and regulatory frameworks governing RWE generation and use across major markets (e.g., US, EU, APAC) You have working knowledge of health authority and HTA evidence expectations (e.g., EMA, FDA, NICE, G-BA, CADTH), particularly where RWE contributes to demonstrating treatment value, real-world effectiveness, or addressing uncertainties in clinical trials You have proficiency with medical evidence planning and insight-generation tools, including structured evidence planning frameworks, RWD portals, and data catalogs used to identify and evaluate internal and external evidence assets and have experience in developing and managing NIS, RWD, and data reuse projects, including protocol development and result dissemination. Relocation Benefits are not available for this job posting. The expected salary range for this position based on the primary location of Mississauga is 136,936.00 and 179,728.50 of hiring range. Actual pay will be determined based on experience, qualifications, and other job-related factors as determined by the company. We use artificial intelligence to screen, assess or select applicants for this role. This posting is for an existing vacancy at Hoffmann-La Roche Ltd. Who we are A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact. Let’s build a healthier future, together. Roche is an Equal Opportunity Employer. We believe it’s urgent to deliver medical solutions right now – even as we develop innovations for the future. We are passionate about transforming patients’ lives. We are courageous in both decision and action. And we believe that good business means a better world. That is why we come to work each day. We commit ourselves to scientific rigor, unassailable ethics, and access to medical innovations for all. We do this today to build a better tomorrow. We are proud of who we are, what we do, and how we do it. We are many, working as one across functions, across companies, and across the world. We are Roche.

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