Job Description Kickstart Your Career at Vertex!  Are you ready to make a real impact? At Vertex, our mission is to tackle serious diseases and to change lives, for the better, for the future. Our aim is to give you the skills, insights, and career guidance to be an important part of that future; to turn your potential into progression. As a Vertex intern or co-op, you’ll work on meaningful projects, collaborate with talented teams, and learn from industry leaders. We’re passionate about innovation, inclusion, and supporting your growth—inside and outside the lab.  Why Vertex?  Real Projects: You’ll work on assignments that make a real impact, not just busy work.  Mentorship & Networking: Connect with leaders and peers who want to see you succeed through professional networks, connections, and collaborations that will shape your longer-term career.  Flexible & Supportive: We offer flexible work options with Flex @ Vertex and prioritize your wellbeing.  Inclusive Culture: Collaboration and inclusion are embedded in everything we do.  Career Launchpad: Build skills, explore career paths, and get guidance for your future career.  Your Impact The Vertex DMPK Bioanalysis Intern is an 11-week experiential training program for students enrolled in a degree program. If you are passionate, collaborative, and growth-minded, an intern at Vertex will help you gain meaningful experience in our Preclinical Sciences functional areas and serve as a launchpad for your career. The application deadline for this internship is January 15th. Please note that Vertex reviews applications on a rolling basis and reserves the right to close this job posting prior to the listed deadline. Applicants can expect to receive an update about their application before or shortly after the application deadline. Ready to apply? Submit your application and let’s turn possibilities into reality!  What you will be doing:  The DMPK bioanalysis group is responsible for developing assays to support preclinical study analysis for multiple therapeutic modalities and programs. This position will be directly involved in the development of a ligand-binding assay and will provide experience in bioanalytical method development, including assay design, optimization, and data analysis. The intern will work with the team to apply relevant bioanalytical guidelines and document the development process. Key Responsibilities: Support the development and optimization of a ligand-binding assay. Plan and conduct experiments with guidance from the bioanalytical team. Evaluate assay performance, including sensitivity, precision, and reproducibility. Analyze results, troubleshoot technical challenges, and recommend next steps. Document methods, experiments, and results in accordance with relevant bioanalytical guidelines and Vertex documentation policies. Present findings and progress updates to the team. Qualifications: Education: Currently enrolled in a bachelor’s or master’s degree program in biochemistry, biology, biotechnology, chemistry, pharmacology, or a related life-sciences field. Experience: No prior industry experience required. At least one laboratory course or research experience involving biochemical or biological experiments is expected. Technical skills: Ability to perform basic laboratory techniques, including accurate pipetting, preparing solutions and serial dilutions. Knowledge: Foundational understanding of protein–ligand interactions, assay controls, and basic data analysis. Familiarity with ligand-binding assays is helpful but not required. Technology: Ability to record and analyze experimental data using Microsoft Excel or Graphpad Prism. Experience with Meso Scale Discovery platforms is a plus. Working skills: Strong attention to detail, clear documentation and communication, and the ability to troubleshoot experiments with guidance. Legal authorization to work in the United States, now and in the future. Please note that Vertex does not provide sponsorship for internships/co-ops or entry level roles within this part of the organization. You must be enrolled in an advanced degree program if graduating before May 2027 You must be available to work full-time, 40 hours per week from May – August 2027 Program Details:   Full-time, paid internship $23.00 – $32.00 USD/hour  Program Dates: May – August 2027  Application Deadline: January 15th, 2027 Recruitment Process & Timeline Our recruitment process follows a rolling timeline, with the following anticipated dates: Application Review: December – January Interviews: January – April Offers Extended: January – April Please note that timelines may vary depending on the position and hiring team. At Vertex, we believe that when you feel your best, you can perform at your best. That’s why our US benefits and global well-being resources are designed to support you. Free 24/7 onsite gym access and free access to group exercise classes  Subsidized commuter benefits- transit and parking  Provided meals—free breakfast daily!  Career development opportunities and events, including C Suite engagement  Social events—both intern-only and company-wide  Location-specific perks and extras!  Recognition of National Intern Day  Our Ways of Working  Flex Designation:  On-Site - Boston Flex Eligibility Status:  On-Site: work five days per week on-site with ad hoc flexibility.  Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.   This job posting is for a temporary role with a third-party agency partner that provides services to Vertex.  The individual selected for this role will be offered the role as an employee of that third-party agency; compensation, medical benefits, fringe benefits and other terms and conditions of employment shall be presented by the third-party agency upon offer.  At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients. Pay Range: $0 - $0 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: Hybrid-Eligible Or On-Site Eligible Flex Eligibility Status: In this Hybrid-Eligible role, you can choose to be designated as: 1. Hybrid: work remotely up to two days per week; or select 2. On-Site: work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time. #LI-Hybrid Company Information Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at [email protected] Help Us Achieve Our Mission Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and conditions. The company has approved therapies for cystic fibrosis, sickle cell disease, transfusion-dependent beta thalassemia, acute pain and acromegaly, and it continues to advance clinical and research programs in these areas. Vertex also has a robust clinical pipeline of investigational therapies across a range of modalities in other serious diseases where it has deep insight into causal human biology, including IgA nephropathy, neuropathic pain, APOL1-mediated kidney disease, primary membranous nephropathy, congenital adrenal hyperplasia, ACTH-dependent Cushing's syndrome, autosomal dominant polycystic kidney disease, type 1 diabetes, generalized myasthenia gravis, and myotonic dystrophy type 1. Vertex was founded in 1989 and has its global headquarters in Boston, with international headquarters in London. Additionally, the company has research and development sites and commercial offices in North America, Europe, Australia, Latin America and the Middle East. Vertex is consistently recognized as one of the industry's top places to work, including 17 consecutive years on Science magazine's Top Employers list and one of Fortune’s 100 Best Companies to Work For. For company updates and to learn more about Vertex's history of innovation, visit www.vrtx.com or follow us on LinkedIn, Facebook, Instagram, YouTube, and X We believe our culture is one of Vertex’s greatest strengths and a key enabler of our ability to deliver transformative medicines for patients who need them. Rooted in innovation, purpose and collaboration, our culture empowers people to take smart risks, challenge conventional thinking and do their best work. The diversity of our people is central to that culture. By bringing together individuals with different backgrounds, experiences and perspectives, we foster an environment where new ideas thrive, better decisions are made and breakthrough innovation is possible. We are committed to creating a workplace where everyone feels valued, included and connected to our shared mission, because we know that our unique culture and the collective strength of our people are what set Vertex apart.

Summer Intern 2027, DMPK Bioanalysis.

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